NAD+, short for Nicotinamide Adenine Dinucleotide, is a coenzyme found in every living cell in the body. It plays a critical role in various cellular processes, including energy production, DNA repair, and regulating important signaling pathways. NAD+ is essential for maintaining the health and functionality of cells and has become a topic of great interest in the scientific and medical communities.
One of the main functions of NAD+ is its involvement in cellular metabolism. It facilitates the conversion of nutrients into energy through a process called cellular respiration. NAD+ acts as a coenzyme in key metabolic reactions, such as glycolysis and the citric acid cycle, helping to extract energy from sugar, fats, and amino acids.
Additionally, NAD+ serves as a substrate for enzymes called sirtuins, which play a role in regulating gene expression and maintaining cellular homeostasis. Sirtuins have been implicated in numerous biological processes, including aging, DNA repair, inflammation, and stress tolerance.
Research has shown that NAD+ levels decline with age, leading to a decline in cellular function and an increased susceptibility to age-related diseases. By supplementing with NAD+ precursors such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN), it is possible to increase NAD+ levels in the body and potentially enhance cellular function.
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